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吳烘

   

吳烘

   

副教授

( 06 )-2533131 # 8331

辦公室

T棟1131

E - mail

hungwu@mail.stust.edu.tw

美國密蘇里大學藥理學博士

 

 

研究興趣

在後基因體時代,我的研究規劃主要著重於應用二維電泳的技術平台與結合質譜技術於癌症、藥物作用機轉、訊息傳遞以及基因多形性的研究。這些研究整合分子藥理學、蛋白質化學、藥物化學、分子生物學、生物醫學等相關領域的技術,而研究結果將能加深對基因表達、疾病過程、藥物作用與訊息傳導路徑的了解並有助於研發對各種蛋白質或傳導路徑有選擇性的藥物以應用於疾病診斷和治療。

 

研究專長

分子藥理學、二維電泳、蛋白質體學、訊息傳導

 

   

 

服務機關

職稱

起迄年月

南台科技大學生物科技系

副教授

92/8-至今

嘉南藥理科技大學藥學系

副教授

84/8-92-7

 

 

老師資料更新中

 

 

2002

Hung Wu, Huang-Wei Shen, Ting-Feng Wu, Lawrence F. Brass, and Kuo-Chun Sung (2002) Extracellular Signal-Regulated Kinases and G protein-Coupled Receptors in Megakaryocytic Human Erythroleukemia Cells: Selective Activation, Differential Regulation, and Dissociation from Mitogenesis. J. Pharmcol. Exp. Ther. 300, 339-345.

2001

Ting-Feng Wu, Hong-Hwa Chen and Hung Wu. (2001) Functional characterization of Marek's disease virus (MDV) origin-binding protein (OBP): analysis of its origin-binding properties. Virus Genes 23, 227-239

1996

Halenda, S. P., Wu, H., Jones, A. W., and Shukla, S. D. (1996) Phospholipase D in platelets and megakaryocytic cells. Chemistry and Physics of Lipids 80, 21-26.

1995

Abrams, C. S., Wu, H., Wei, Z., Belmonte, B., White, D., and Brass, L. F. (1995) Pleckstrin inhibits phosphoinositide hydrolysis mediated by G protein coupled and growth factor receptors: A role for N-terminal PH domain of pleckstrin. J. Biol. Chem. 270, 14485-14492

1992

Wu, H., James-Kracke, M. R., and Halenda, S. P. (1992) Direct relationship between intracellular calcium mobilization and phospholipase D activation in prostaglandin E-stimulated human erythroleukemia cells. Biochemistry 31, 3370-3377.

1992

Turner, J. T., Camden, J. M., Kansra, S., Shelton-James, D., Wu, H., and Halenda, S. P. (1992) Potentiation of cyclic AMP production by thrombin in the human erythroleukemia cell line, HEL. J. Pharmacol. Exp. Ther. 263, 708-716.

1991

Wu, H., Turner, J. T., and Halenda, S. P. (1991) Activation of phospholipase D by E series prostaglandins in human erythroleukemia cells. J. Pharmacol. Exp. Ther. 258, 607-612.

1991

Wu, H., Franklin, C.C., Kim, H. D., and Turner, J. T. (1991) Regulation of calcium activated potassium efflux by neurotensin and other agents in HT-29 cells. Am. J. Physiol. 260, C35-C42.

1988

Rehm, A. G., Wu, H., and Halenda, S. P. (1988) Guanine nucleotides inhibit agonist-stimulated arachidonic acid release in both intact and saponin-permeabilized human platelets. FEBS Lett. 234, 316-320.

 

 

1999

Wu, H. (1999) Stimulation of extracellular signal-regulated kinase by PGE2 and thrombin in human erythroleukemia cells. Southeast Asian-Western Pacific Regional Meeting of Pharmacologists. Abstract P094.

1992

Wu, H. and Halenda, S. P. (1992) Activation of phospholipase D by GTPgS and phorbol ester in permeabilized human erythroleukemia cells. FASEB J. 6, A1922.

1991

Wu, H., Turner, J. T., and Halenda, S. P. (1991) Activation of phospholipase D in human erythroleukemia (HEL) cells by prostaglandin E1 and E2. FASEB J. 5, A479.

1990

Wu, H., Franklin, C. C., Kim, H. D., and Turner, J. T. (1990) Regulation of Ca2+-activated K+ channels by neurotensin and other agents in HT29 human colon cells. FASEB J. 4, 449.

 

 

年度

研究計畫名稱

補助單位

93

南投縣水里鄉發展地方名產-梅肉精緻發展計畫

南投縣水里鄉休閒農業產銷班第二班

 

 

年度

研究計劃名稱

補助單位

95

利用二維電泳探討多酚類物質對lipid raft蛋白質體的影響95-2313-B-218-001-

國科會

93

梅子濃縮萃取液(梅肉精)對心血管疾病預防作用之開發研究NSC-93-2622-B-218-003-CC3

國科會.奕青農場

93

應用新穎分子生物學與蛋白質體學的技術平台以開發抗氣喘保健食品NSC-93-2622-B-218-003

國科會

 

 

 

老師資料更新中

 

 

 

老師資料更新中

 

 

 

老師資料更新中